Cinnamic acids and derivatives
Medchemexpress LLC Ozagrel hydrochloride | 78712-43-3 | MFCD06795644 | >98.0% | 10 MG
Ozagrel hydrochloride is the hydrochloride salt of ozagrel, a selective thromboxane A2 (TXA2) synthase inhibitor used in preclinical research to study platelet aggregation, ischemic stroke, asthma, and thromboembolic disease.
- Selective thromboxane A2 (TXA2) synthase inhibitor with reported IC50 ~11 nM.
- Reduces thromboxane A2 production, leading to anti-platelet aggregation and vasodilation.
- Hydrochloride salt supplied as a powder suitable for in vitro and in vivo research.
- Typical molecular weight 264.71 g/mol and formula C13H13ClN2O2.
- High purity commonly reported as ≥98% (verify with vendor for specific lot).
- Store powder at -20°C for long-term stability; in solution, store at -80°C.
Medchemexpress LLC α-acetamidocinnamic acid | 5469-45-4 | MFCD00008680 | 99.5% | 205.21 g/mol | C11H11NO3 | 50 G
α-Acetamidocinnamic acid is a naturally occurring alkaloid isolated from Cinnamomum cassia bark, supplied as a research-grade solid. It has formula C11H11NO3 and molecular weight 205.21 g/mol, and is provided with batch-specific quality data suitable for laboratory use.
- Naturally occurring alkaloid isolated from plant bark.
- Supplied as an off-white to light-yellow solid for easy handling.
- High purity suitable for research applications.
- Provided with certificate of analysis for batch verification.
- Useful as a building block or reference standard in chemical research.
![Medchemexpress LLC 2-Propenamide, N-[2-hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenyl-, (2E)- | 456-12-2 | MFCD00048045 | 99.8% | 297.35 g/mol | C18H19NO3 | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000209428.png-250.jpg)
Medchemexpress LLC 2-Propenamide, N-[2-hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenyl-, (2E)- | 456-12-2 | MFCD00048045 | 99.8% | 297.35 g/mol | C18H19NO3 | 1 G
Aegeline is an alkaloid reference standard intended for research use that mimics the yeast SNARE protein Sec22p and suppresses α-synuclein and Bax toxicity in yeast while exhibiting antioxidant activity.
- Alkaloid reference standard for research use.
- Cas number: 456-12-2.
- Chemical formula: C18H19NO3; molecular weight: 297.35 g/mol.
- Purity 99.81% (as provided on the certificate of analysis).
- Form: white to off-white solid powder.
- Solubility: soluble in DMSO (100 mg/mL); in vivo formulations listed for dosing preparations.
- Storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solution at -80°C or -20°C for shorter periods.
- Pack size: 1 g.
Chem-Impex International, Inc. trans-Ferulic acid | 1135-24-6 | MFCD00004400 | 100G
trans-Ferulic acid, 1135-24-6, MFCD00004400, 100G
Selleck Chemical LLC Tyrphostin AG-528
Tyrphostin AG-528 (Tyrphostin B66) is a potent inhibitor of epidermal growth factor receptors (EGFR) and ErbB2/HER2 with IC50 of 4 9 M and 2 1 M respectively Tyrphostin AG-528 exhibits anticancer activity
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 100 MG
p-Coumaric Acid Ethyl Ester is a non-competitive, reversible inhibitor of tyrosinase, used in the development of medicines, cosmetics, and fruit preservation products derived from pollen. It functions by quenching the intrinsic fluorescence of the enzyme and inducing conformational changes in the catalytic domain of tyrosinase, which alters the binding affinity of L-tyrosine without binding to the copper ion.
- Tyrosinase inhibition: Non-competitive, reversible inhibitor with IC50 = 4.89 μg/mL and Ki = 1.83 μg/mL
- Shows anti-platelet activity in rabbit platelet-rich plasma (IC50 = 130.4 μM)
- Used in the development of medicines, cosmetics, and fruit preservation products
- High purity of 99.19%
- Molecular weight: 192.21
- Chemical formula: C11H12O3
- Appearance: Solid, light yellow to light brown
- Soluble in DMSO at 100 mg/mL (520.26 mM)
Pfaltz & Bauer 2 4-Dimethoxycinnamic Acid 97 25G | 6972-61-8
2 4-Dimethoxycinnamic Acid 97 25G | 6972-61-8
Apexbio Technology LLC Entacapone 130929-57-6 10mM (in 1mL DMSO)
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
Medchemexpress LLC Ferulic acid 4-O-sulfate | 86321-29-1 | 98.07% | 274.25 | 100 MG
Ferulic acid 4-O-sulfate, also known as Ferulic acid 4-sulfate, is a metabolite of Ferulic acid that has been observed to relax arteries and decrease blood pressure in mice.
- In vitro: This compound, at concentrations ranging from 0.1 to 30 μM, elicited significant concentration-dependent relaxations in the aorta, femoral, and saphenous arteries of mice.
- In vivo: When administered intravenously to male Swiss mice at dosages of 16.13 and 161.3 μg/kg, ferulic acid 4-O-sulfate demonstrated the ability to relax arteries and lower blood pressure, with a significant decrease in mean arterial pressure (MAP) observed immediately post-injection.
Chem-Impex International, Inc. trans-Ferulic acid | 1135-24-6 | MFCD00004400 | 25G
trans-Ferulic acid, 1135-24-6, MFCD00004400, 25G
Selleck Chemical LLC 2-Methoxycinnamic acid
2-Methoxycinnamic acid (AI3-11206) is a cinnamic acid with magnetic properties